Streamlining B. subtilis Genome: One Goal Is Better Productivity
نویسندگان
چکیده
منابع مشابه
Enhanced Recombinant Protein Productivity by Genome Reduction in Bacillus subtilis
The emerging field of synthetic genomics is expected to facilitate the generation of microorganisms with the potential to achieve a sustainable society. One approach towards this goal is the reduction of microbial genomes by rationally designed deletions to create simplified cells with predictable behavior that act as a platform to build in various genetic systems for specific purposes. We repo...
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متن کاملStreamlining and simplification of microbial genome architecture.
The genomes of unicellular species, particularly prokaryotes, are greatly reduced in size and simplified in terms of gene structure relative to those of multicellular eukaryotes. Arguments proposed to explain this disparity include selection for metabolic efficiency and elevated rates of deletion in microbes, but the evidence in support of these hypotheses is at best equivocal. An alternative e...
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ژورنال
عنوان ژورنال: Microbe Magazine
سال: 2013
ISSN: 1558-7452,1558-7460
DOI: 10.1128/microbe.8.55.1